Sublingual immunotherapy (SLIT) is an allergy tablet given under the tongue. This should only be taken when under the care of a doctor who is trained on this medicine. You will take the first dose at the clinic. If there are no problems, you will take all other doses at home.

Mild Reactions

You may have some mild reactions in the first few days to weeks after starting SLIT. These symptoms are brief and go away without any special treatment. Symptoms you may have include:

  • Itching or discomfort in your mouth

  • Mild abdominal pain

  • Mild itching of the eyes, nose, ears or throat

Moderate to High-Risk Reactions

There is a chance you may have serious reactions that require urgent treatment. These include, but are not limited to:

  • Moderate to severe itchy eyes, nose, ears or throat

  • Stuffy nose, sneezing, runny nose

  • Mouth, nose, or moderate to severe belly pain

  • Cough

  • Swelling of the lips, tongue, or throat

  • Trouble breathing

  • Nausea and vomiting.

  • Hives and/or itching all over your body

  • Anaphylaxis, a rare life-threatening reaction

Epi-pen

Due to the risk of a bad reaction, you must agree to have self-injectable epinephrine (Epi-pen) on hand with each dose of SLIT.

After Dose

After you receive the first dose, you must wait in the doctor’s office for at least 30 minutes to monitor for any serious reactions.

If you are a minor, a parent or legal guardian must stay with you for the full 30 minutes.