Leave the bandage on for 48 hours after the procedure. Keep the dressing clean and dry until then. If the dressing comes off sooner, replace it with a new dressing or a Band-Aid®.

After 48 Hours

Remove the dressing and clean the wound. Clean the wound daily until healed or stitches are removed.
To clean and care for the wound:

  1. Wash your hands.

  2. Carefully wash the area with a gentle, fragrance free soap. Rinse well.

  3. Let area air dry or gently pat dry.

  4. Any crust will slowly come off as you clean daily. Do not force crust off.

  5. Apply Vaseline® to the wound after cleaning.

  6. Cover with Band-Aid® or other dressing. If the Band-Aid® is irritating your skin, try putting the Band-Aid® in different directions. You could also make a dressing with a small, nonstick pad held in place by paper tape. You may apply over-the-counter hydrocortisone cream to irritated skin. Do not put on biopsy or surgical site.


  • Swimming, hot tubs, soaking the wound in a bath (a gentle shower is okay).

  • Too much stretching or exercising of areas in or close to the wound.

  • Exposing wound to dust or dirt.


Some wounds bleed or ooze during the first 24 hours. Bleeding may be worse if you are taking a blood thinner.
If the wound does bleed and you see blood soaking through the bandage, do not remove the bandage. Tips to stop the bleeding:

  • Cover the bandage with a clean gauze pad and apply constant firm pressure for at least 20 minutes, without letting up.

  • Raise the wound site using a pillow or sitting position if the lesion is on the head.

  • Apply an ice pack or cold compresses over the covered wound dressing.

If bleeding does not stop after 20 minutes of constant pressure, call the clinic. If clinic is closed, go to the closest emergency room.

Normal Changes

  • Redness and swelling around the wound site the first few days, this will get better over time.

  • Tenderness is normal during the first days but should also get better with time.

  • Clear or light-yellow drainage.

Signs of Infection

  • Spreading of redness and/or swelling at surgical site 1 to 2 days after the procedure.

  • It is more tender after 1 to 2 days.

  • Fever (greater than 100.4°F) with 2 readings, 4 hours apart.

  • Increased warmth at the site.

  • Green or yellow discharge.


Mild pain is normal, especially with activity. Take Tylenol® every 4 to 6 hours as needed. Do not take aspirin or ibuprofen products for 72 hours after the procedure.

Stitches and Scars

Stitches can sometimes come out or the wound edges can come apart before stitches are removed. If that happens, continue wound care as before. The wound will heal on its own. No new stitches will be placed.

You will have a scar at the wound site. Some scars may thicken, and others may take several months to flatten out. Most scars will improve over time but may take several months.

Tips for the First 1 to 2 Days

If your wound is on your face, head or neck:

  • Sleep with your head up on 2 pillows, so you will have less swelling.

  • Avoid bending with your head below your heart.

If your wound is on your arm or leg:

  • Keep your arm or leg raised as much as you can.

  • Use ace or elastic wraps to decrease swelling and support the areas during activity.

Who to Call

If you have any questions about the care of your biopsy or surgical site, contact the clinic that did the procedure.

Junction Rd Medical Center
451 Junction Road
Madison, WI 53717
(608) 263-6226

E. Terrace Dr Medical Center
5249 East Terrace Drive
Madison, WI 53718
(608) 265-1288

1 S. Park Medical Center- Dermatology
1 S. Park Street
Madison, WI 53715
(608) 287-2450

Toll free: 800-323-8942

If you are a patient receiving care at UnityPoint – Meriter, Swedish American or a health system outside of UW Health, please use the phone numbers provided in your discharge instructions for any questions or concerns.